Datasets and tools
C9orf72 hexanucleotide repeat expansions impair microglial response in ALS
Masrori P, Bijnens B, Fumagalli L, Davie K, Poovathingal SK, Meese T, Storm A, Hersmus N, Fazal R, van den Biggelaar D, Asselbergh B, Gruel R, Van Den Daele J, Denton H, Miquel PP, Manzella S, De Vos WH, Chandran S, Van Den Bosch L, Thal DR, Mancuso R, Van Damme P.
Microglia heterogeneity, modeling and cell-state annotation in development and neurodegeneration
Fumagalli L, Nazlie Mohebiany A, Premereur P, Polanco Miquel P, Bijnens B, Van de Walle P , Fattorelli N & Mancuso R
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related Aβ pathology
Mancuso R, Fattorelli N, Martinez-Muriana A, Davis E, Wolfs L, Van Den Daele J, Geric I, Premereur J, Polanco P, Bijnens B, Preman P, Serneels L, Poovathingal S, Balusu S, Verfaillie C, Fiers M, De Strooper B.
Stem-cell-derived human microglia transplanted in mouse brain to study human disease
Mancuso R, Van Den Daele J, Fattorelli N, Wolfs L, Balusu S, Burton O, Liston A, Sierksma A, Fourne Y, Poovathingal S, Arranz-Mendiguren A, Sala Frigerio C, Claes C, Serneels L, Theys T, Perry VH, Verfaillie C, Fiers M, De Strooper B.
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice
Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, Mudher A, Vicente-Rodriguez M, Parker CA, Simmons C, Cash D, Richardson J; NIMA Consortium, Jones DNC, Lovestone S, Gómez-Nicola D, Perry VH.