Datasets

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Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related Aβ pathology

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MancusoR, FattorelliN, Martinez-MurianaA, DavisE, WolfsL, Van Den DaeleJ, GericI, PremereurJ, PolancoP, BijnensB, PremanP, SerneelsL, PoovathingalS, BalusuS, VerfaillieC, FiersM, De Strooper B.

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Stem-cell-derived human microglia transplanted in mouse brain to study human disease

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Mancuso R, Van Den Daele J, Fattorelli N, Wolfs L, Balusu S, Burton O, Liston A, Sierksma A, Fourne Y, Poovathingal S, Arranz-Mendiguren A, Sala Frigerio C, Claes C, Serneels L, Theys T, Perry VH, Verfaillie C, Fiers M, De Strooper B.

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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

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Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, Mudher A, Vicente-Rodriguez M, Parker CA, Simmons C, Cash D, Richardson J; NIMA Consortium, Jones DNC, Lovestone S, Gómez-Nicola D, Perry VH.